4-AMINO-3-FLUOROBENZOIC ACID

4-AMINO-3-FLUOROBENZOIC ACID - Names and Identifiers

Name	4-amino-3-fluorobenzoic acid
Synonyms	NSC 25758 4-AMINO-3-FLUOROBENZ 4-Amino-3-Fluorobenzoic 4-amino-3-fluoro-benzoicaci 4-AMINO-3-FLUOROBENZOIC ACID 3-FLUORO-4-AMINOBENZOIC ACID 4-amino-3-fluorobenzoic acid 4-AMINO-3-FLUOROBENZENECARBOXYLIC ACID
CAS	455-87-8
EINECS	207-250-1
InChI	InChI=1/C7H6FNO2/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3H,9H2,(H,10,11)
InChIKey	JSKXHTHMCCDEGD-UHFFFAOYSA-N

4-AMINO-3-FLUOROBENZOIC ACID - Physico-chemical Properties

Molecular Formula	C7H6FNO2
Molar Mass	155.13
Density	1.430±0.06 g/cm3(Predicted)
Melting Point	215-218°C
Boling Point	320.8±27.0 °C(Predicted)
Solubility	Hot Water
Appearance	Fine Needles
Color	White to Light yellow to Light orange
pKa	4.52±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
MDL	MFCD01660374

4-AMINO-3-FLUOROBENZOIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
RTECS	DG2525000
Hazard Class	IRRITANT

4-AMINO-3-FLUOROBENZOIC ACID - Introduction

4-amino-3-fluorobenzoic acid is an organic compound with the chemical formula C7H6FNO2. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: 4-amino-3-fluorobenzoic acid is a white crystalline solid.
-Melting point: about 212 ℃.
-Solubility: Soluble in water and some organic solvents at room temperature, such as ethanol and ether.

Use:
-Chemical synthesis: 4-amino-3-fluorobenzoic acid can be used as raw materials and intermediates in organic synthesis. It can be used to synthesize other organic compounds, such as drugs, pesticides, dyes, polymers, etc.
-Pharmaceutical application: This compound has certain biological activity, so it also has potential uses in pharmaceutical research and development.

Preparation Method:
The preparation method of 4-amino-3-fluorobenzoic acid is generally carried out by the following steps:
1.2-amino -1-fluorobenzene (2-aminofluorobenzene) reacts with sodium cyanate to generate 2-amino -1-fluorobenzonitrile (2-aminofluorobenzobenzene).
2. heating hydrolysis of 2-amino -1-fluorobenzonitrile to obtain 4-amino-3-fluorobenzoic acid.

Safety Information:
- 4-amino-3-fluorobenzoic acid is generally stable and relatively safe under normal use conditions.
-However, it may irritate the eyes, skin and respiratory tract, so direct contact should be avoided. Wear appropriate personal protective equipment such as gloves, goggles and respiratory protection.
-In the event of accidental contact or inhalation, immediately flush the affected area with clean water and seek medical assistance.

Last Update：2024-04-09 20:49:11